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Tuesday, May 5, 2009

Cerebral Tumour detected by Quantum-Biophysical Semeiotics since its Inherited Real Risk.


From its initial stage, brain oncological process, occupying space, provokes local circulatory modifications of both hyperemic and ischemic type, secondary to biochemical and/or compressive events. Quantum Biophysical Semeiotics (BS) permits doctor to observe microcirculatory phenomena as well as variations of the tissue pH at the bed-side (See: my website (1-8).

Furthermore, the cerebral potentials (1, 5), whether spontaneous or evoked, clearly altered or totally absent in case of tumour, may be evaluated “quantitatively” with the aid of BS, even in early stage.

In following, it is referred both the usefulness and reliability of such as semeiotics in diagnosing cerebral tumour, even in the initial phase of Inherited Real Risk (6, 9-14).


As regards QBS of cerebral tumour, it is enough to know, from the technological point of view, the auscultatory percussion of the stomach (in above-cited website, Technical Page N° 1), which is performed with digital percussion, directly and “gently”, applied on abdominal skin, from outer areas towards the bell-piece of stethoscope along radial and centripetal lines, as indicated in Fig.1

When percussion is applied on organ or viscera skin projection areas, percussory sound is perceived as altered, modified, dull or hyperfonetic, in relation to the density of investigated structure, in any case “as originating from a site close to the doctor’s ears”.

Obviously, a complete knowledge of QBS permits doctor to gather further information.

There are a large number of other Quantum Biophysical Semeiotics data referring to cerebral tumour; however, as follows, are referred only some unavoidable signs, easy to evaluate and reliable in bed-side detecting cerebral tumour.

Quantum Biophysical Semeiotic Signs of Cerebral Tumour

At first doctor has to ascertain the so-called oncological terrain (6), conditio sine qua non of malignancy , and is composed particularly of:

1) Congenital Acidosic Enzyme-Metabolic Histangiopaty (CAEMH). Briefly, digital pressure of “middle” intensity upon skin projection area, e.g., of temporal convolutions (temporal lobe), brings about a gastric aspecific reflex more intense when right cerebral lobe is stimulated, due to the right cerebral dominance, typical for CAEMH: dominance of the right Planum temporale. (2,10).

2) Psycho-neuro-endocrine-immunological system dysfunction (6): in a easy manner doctor ascertains this pathological condition inviting the patient to close intensively his (her) eyes (= dark increases melatonin secretion, which in turns stimulates the secretion of endogenous oppioids, the so-called orchestra directors of immunological system): after 15 sec.

In health, digital pressure of small intensity, directly applied ,e.g., on a breast gland, causes gastric aspecific reflex with latency time of 3 sec.( i.e. acute antibody synthesis syndrome).

On the contrary, when eyes are open, latency time is 6 sec.(i.e. chronic antibody synthesis syndrome).

3) Suck simulated test to provoke Prolactin Secretion: repeated palpation of mammary gland provokes, in healthy individuals of both sexes and of middle age, gastric aspecific reflex of exact 6 sec. duration. In case of inflammatory process, as flu, however, duration results prolonged (7 sec. exactly). Finally, in subject with oncological terrain duration appears ³ 7 sec., in a direct relation to the degree of the psycho-neuro-endocrine-immunological system dysfunction.

The duration is very prolonged, of course, in case of tumour. Physiologically, the test presents the most elevated duration in pregnacy, due to the particular endocrine situation, since initial stage.

In a patient, who presents with a symptomatology suggestive of cerebral tumour (or in asymptomatic patient, of course) other QBS signs are properly investigated.

An interesting sign, particularly useful and reliable in bed-side detecting the presence of “something wrong” in the head is the following:

4) Aspecific gastric-oculo reflex. In health, the appearance of gastric aspecific reflex, physiologically symmetric, during digital pressure on the eye-ball (when patient’s eyes are closed, naturally) after a latency time 6 sec. and 1-2 cm. in intensity.

On the contrary, in case of cerebral neoplasia as well as other cerebral disorder, when pressure is exerted on the homolateral eye-ball, doctor observes initially a gastric aspecific reflex (lt 3 sec.; intensity > 2 cm.; duration 3 sec.), and, soon thereafter, the “autoimmune syndrome”: gall-bladder and stomach contract (gastric tonic contraction = GTC) and spleen become empty of blood: in practice, it is sufficient for the diagnosis ascertaining GTC.

In diagnosing clinically the cerebral tumour, a major role is played by the:

5) Cerebral-gastric aspecific reflex: finger-pulp as well as finger-nail pressure (type I and type II, respectively) on skin projection area of the tumour provokes the “autoimmune syndrome”, as described above. Finally, in the presence of cerebral malignancy, there is always the:

6) Reticulo-Endothelial System Hyperfunction Syndrome (RESHS) of “complete” type, that corresponds to BSR, but it is more sensitive and sensible.

In health, finger-pulp pressure on the middle line of sternal-body, iliac crests and skin projection area of the spleen causes aspecific gastric reflex after a latency time = 10 sec.exactly.

On the contrary, in case of cerebral cancer latency time results lowered, in relation to disorder seriousness.

Finally, one must remember that acute phase proteins are augmented and both the acute autoantibody secretion syndrome and circulating immuncomplex syndrome (boxer’s test, i.e. patient is clenching his or her fists, brings about gastric tonic contraction -GTC-, after appearing gastric aspecific reflex lasting 3 sec.) are present (2-9).

Due to the lack of reader’s Quantum Biophysical Semeiotic knowledge, at this moment I do not illustrate numerous other signs of cerebral tumour.

To summarize, QBS diagnosis of cerebral tumour is based (at least) on the following signs:

1) Congenital Acidosic Enzymo-Metabolic Histangiopathy (CAEMH), which plays a primary role in the psycho-neuro-endocrine-immunological system dysfunction, I termed as Oncological Terrain.

2) Oncological terrain (1-6);

3) Reticulo Endothelial System Hyperfunction Syndrome (RESHS) type “complete” (4);

4) Oculo-gastric aspecific reflex and then gastric tonic contraction (GTC) (1-6, 9,14);

5) Cerebro-gastric aspecific reflex (type I and II) followed by GTC(1-6, 9,14);

5) Acute phase proteins augmentation (3, 6);

6) Acute autoantibody secretion syndrome ((1-6, 9,14);

7) Circulating Immunocomplex Syndrome, above-described .

In addition, a lot of clinical microangiological signs, gathered at the bed-side by evaluating both vasomotility and vasomotion of cerebral microvessels, are actually interesting and precious in recognizing also cerebral malignancy since its first stage: due to reader’s inadequate Quantum Biophysical semeiotic knowledge: I will illustrate these signs next, in the future.

As far as Cerebral Evoked Potentials is concerned, it is well-known that visive, auditory and somato-sensorial stimuli, through nervous in-puts, provoke physiologically the activation of corresponding nervous centres by mean of depolarization. Consequently, local cerebral microcirculation results more or less activated, allowing doctor to evaluate these events by means of Quantum Biophysical Semeiotics.

If a subject looks at a light source, e.g., due to the stimulation of optic channels, impulses reache the bilateral cortical-occipital region and activate it, that is, they evoke electrical potentials, demonstrating the anatomo-functional integrity of such nervous structures. Analogously, auditive and somato-sensorial stimuli (the later really more practical and therefore advisable) provoke electrical potentials, obviously in corresponding cortical centres.

Experimental (an individual is invited, e.g., to move or to “think of moving “ a hand) and clinical (epileptic focus, e.g.) evidence suggests that the cerebral evoked potentials can be evaluated by means of Quantum Biophysical Semeiotics, because of the hemoreological and microcirculatory phenomenology of the active hyperemic areas (In termes of Cinical Microangiology: activation type I, associated, of both vasomotility and vasomotion). In fact, the finger-pulp pressure of “middle” intensity on the cutaneous projection of an activated cerebral zone causes gastric aspecific reflex. Consequently, in case of cerebral malignancy, the absence of the cerebral evoked potentials shows the suffering of precise nervous channels, due to a disorder, easily ascertained at the bed side.


1) Stagnaro S., Stagnaro-Neri M. Auscultatory Percussion in Detection Focal Liver Lesions even Clinically Silent. Acta Med. Medit. 8, 89-94, 1992.

2) Stagnaro S., Auscultatory percussion of the cerebral tumour: Diagnostic importance of the evoked potentials, Biol. Med., 7, 171-175, 1985.

3) Stagnaro-Neri M., Stagnaro S., Cancro della mammella: prevenzione primaria e diagnosi precoce con la percussione ascoltata. Gazz. Med. It. – Arch. Sc. Med. 152, 447, 1993.

4) Stagnaro S., Sindrome percusso-ascoltatoria di Iperfunzione del Sistema Reticolo-IstiocitarioMin. Med. 74, 479, 1983 [MEDLINE].

5) Stagnaro S., Percussione Ascoltata degli Attacchi Ischemici Transitori. Ruolo dei Potenziali Cerebrali Evocati. Min. Med. 1985, 76, 1211 [MEDLINE].

6) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica Biofisica. Il Terreno oncologico”. Travel Factory SRL., Roma, 2004.

7) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine. Ediz. Travel Factory, Roma, 2004.

8) Stagnaro Sergio. Bed-Side Prostate Cancer Detecting, even in early stages (“Real Risk” of Cancer): BMC Family Practice, 6:24 doi:10.1186/1471-2296-6-24

9) Sergio Stagnaro Mitochondrial Bed-Side Evaluation: a new Way in the War against Cancer (21 December 2005). Cancer Cell International

10) Stagnaro S. Genes and Cancer: a clinical view-point. The Oncological Terrain. BioMed Central Informatics, 2004.

11) Stagnaro S., Stagnaro-Neri M., Oncological Terrain, conditio sine qua non of Oncogenesis, GUT, 2004.

12) Stagnaro Sergio. "Genes, Oncological Terrain, and Breast Cancer", World Journal of Surgical Oncology. 2005,

13)Stagnaro Sergio. GPs , Quantum Biophysical Semeiotics, and bedside cancer diagnosis. 08 July 2007, International Seminar of Surgical Oncology,

14) Stagnaro Sergio. Overloking Oncological Terrain and oncological Real Risk, no paper is up-dated! 18 January 2008 Ann. Intern Med.

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