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Sunday, March 22, 2009

Pollio’s Sign* in bedside Recognizing renal Cancer, since its initial Stage of Inherited, Oncological Real Risk.

Sergio Stagnaro MD
Founder of Quantum Biophysical Semeiotics
Biophysical Semeiotics Research Laboratory
Riva Trigoso (Genova) Italy

Renal Cancer (RC) represent about 3% of all malignancies and are continuously increasing: in Italy 4.000 persons are involved yearly by RC, and 27.000 new cases are diagnosed in Europe. The early diagnosis is the conditio sine qua non of the best therapeutic results. Unfortunately, RC are mainly recognized later, since for years or decades they are silent from the clinical syntomatology, in spite is originates as renal Inherited Oncological Real Risk. Analogously to all other malignancy, RC may occur exclusively in individuals involved by both Oncological Terrain “and” Oncological Terrain-Dependent Inherited Oncological Real Risk in the kidney, bedside recognized even at birth with the aid of Quantum Biophysical Semeiotics (1-7).
In health, “light-moderate” persisting stimulation by cutaneous pintching of renal trigger-points, i.e., VIII-X thoracic dermatomeres (= lateral abdominal quadrants), after exact 8 sec. latency time, brings about aspecific gastric reflex: in the stomach, both fundus and body dilate, while antral-pyloric region contracts: Reflex duration lasts LESS than 4 sec.: such as parameter value, paralleling local Microcirculatory Functional Reserve, plays a central role in bedside diagnosing RC, starting from the first stage of Inherited Oncological Real Risk.
On the contrary, in individual involved by urinary way cancer Inherited Oncological Real Risk, the identical stimulation causes aspecific gastric reflex, showing normal latency time (NN = 8 sec.), BUT its duration is 4 sec. or more, i.e. pathological. Really, these two parameter values are inversely and respectively directly related to the seriousness of underlying disorders. Immediately there after, appears tonic Gastric Contraction, characteristic of tumoural lesion: Pollio’s Sign..
Due to no local realm of biological systems (8-10), when renal trigger-points stimulation is “intense”, all components of urinary tract are “simultaneously” stimulated: in health, reflex latency time raises cannot brings about gastric aspecific reflex, allowing rapidly doctor to exclude urinary tract lesion!
On the contrary, in case of renal cancer, even in the stage of Inherited Oncological Real Risk, simultaneously appears the reflex, followed suddenly by tonic gastric contraction, typical of lesion, oncological in nature, because locally free energy is increased, due to type I, associated, microcirculatory activation (3-7).
To summarize, in subject involved by both Oncological Terrain and Inherited Oncological Real Risk in whatever part of urinary system (kidney, urther, urinary bladder, prostate), “intense” stimulation of a SINGLE trigger-point causes simultaneously intense aspecific gastric reflex, immediately followed by tonic Gastric Contraction: Pollio’s Sign, which surely will play a paramount role in RC as well as in urinary tract malignancies primary prevention. Subsequently, physicians will localized tumoural lesion with the aid of a lot of well-known biophysical-semeiotic signs (1-7)

* Pollio’s Sign. In memory of my dear friend, Fabrizio Pollio MD, brilliant gynaecologist surgeon, dead at age of 34 years for renal cancer.


1) Stagnaro Sergio. (7 February 2008). Bedside diagnosing prostate cancer inherited oncological real risk and its therapy. Annals of Internal Medicine.
2) Stagnaro Sergio. Oncogenesis is possible exclusively in individuals Oncological Terrain-positive. 2007.
3) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeiotica Biofisica. Il Terreno Oncologico. Ed. Travel Factory, Roma, 2004.
4) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004.
5) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine. Travel Factory, Roma, 2004.
6) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004.
7) Stagnaro Sergio. Oncological Terrain and Inherited Oncological Real Risk: New Way in Malignancy Primary Prevention and early Diagnosis. International Seminars in Surgical Oncology, 2007.
8) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica: Realtà non-locale in Biologia. Dicembre 2007,,
9) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica Quantistica.
10) Stagnaro Sergio. Esperimento di Lory e Crisi dei Fondamenti della Medicina Occidentale. 17 Febbraio 2008

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